Signal peptides, such as palmitoyl tripeptide-1, operate as messengers to cells, triggering collagen formation and increasing skin firmness. Palmitoyl tripeptide-1 is a short signal peptide comprising three amino acids having the amino sequence glycine-histidine-lysine (GHK). To improve skin penetration and oil solubility, GHK is linked to palmitic acid (a fatty acid). Palmitoyl tripeptide-1 instructs cells to produce more collagen, hence boosting new collagen creation. It takes at least a month or longer to notice obvious improvements from new collagen. They are also added to certain topical serums used after micro-needling or superficial laser treatments to boost peptide penetration and aid in skin recovery.
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